4-[4-(Trifluoromethyl)phenyl]aniline

4-[4-(Trifluoromethyl)phenyl]aniline - Names and Identifiers

Name	4'-(Trifluoromethyl)biphenyl-4-amine
Synonyms	AKOS BAR-0143 4-AMINO-4'-TRIFLUOROMETHYLDIPHENYL 4-[4-(Trifluoromethyl)phenyl]aniline 4'-(Trifluoromethyl)biphenyl-4-amine 4'-(TrifluoroMethyl)-biphenyl-4-aMine 4'-TRIFLUOROMETHYL-BIPHENYL-4-YLAMINE 4'-(Trifluoromethyl)-biphenyl-4-amine 4-Amino-4''-(trifluoromethyl)-biphenyl 4'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-4-AMINE [1,1'-Biphenyl]-4-amine, 4'-(trifluoromethyl)-
CAS	57688-34-3
InChI	InChI=1/C13H10F3N/c14-13(15,16)11-5-1-9(2-6-11)10-3-7-12(17)8-4-10/h1-8H,17H2

4-[4-(Trifluoromethyl)phenyl]aniline - Physico-chemical Properties

Molecular Formula	C13H10F3N
Molar Mass	237.22
Density	1.245±0.06 g/cm3(Predicted)
Boling Point	303.1±37.0 °C(Predicted)
Flash Point	134.6°C
Vapor Presure	0.00095mmHg at 25°C
pKa	3.90±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.543

4-[4-(Trifluoromethyl)phenyl]aniline - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

4-[4-(Trifluoromethyl)phenyl]aniline - Introduction

4 '-(Trifluoromethyl)biphenyl-4-amine is a chemical substance whose chemical structure is C13H9F3N. The following is a description of some of its properties, uses, methods and safety information:

Nature:
-Appearance: colorless crystal
-Molecular weight: 221.21g/mol
-Melting point: 80-82 degrees Celsius
-Boiling point: 344 degrees Celsius
-Solubility: Soluble in common organic solvents such as methanol, ethanol and dichloromethane

Use:
4 '-(Trifluoromethyl)biphenyl-4-amine has certain biological activity and chemical reaction activity, so it can be used in many fields:
-Drug field: As a drug intermediate, it can be used to synthesize specific drug molecular structures.
-Pesticide field: It can be used to synthesize new pesticide active ingredients.
-Coating and pigment field: It can be used to synthesize new organic pigments and coating ingredients.

Preparation Method:
The preparation method of 4 '-(Trifluoromethyl)biphenyl-4-amine is roughly as follows, but please note that it is carried out under laboratory conditions:
1. A fluorination reaction of biphenyl and trifluoromethane is performed to obtain 4 '-trifluoromethyl-biphenyl.
2. Reaction of 4 '-trifluoromethyl-biphenyl with ammonia to produce 4'-(Trifluoromethyl)biphenyl-4-amine.

Safety Information:
The following safety precautions should be taken when using 4 '-(Trifluoromethyl)biphenyl-4-amine:
-It is an organic compound with certain toxicity. Please take necessary personal protective measures during operation, such as wearing gloves and protective glasses.
-Avoid direct contact with the skin and inhalation of its dust or vapor, avoid eating or swallowing.
-During storage and handling, please keep it away from fire and oxidant.
-Please make sure to operate under proper ventilation conditions to avoid the accumulation of harmful gases.

Please note that the above information is for informational purposes only and specific nature, use and safety information may require more specific information or professional consultation.

Last Update：2024-04-09 20:49:11